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Elettrodeionization (ELDI)
System description


Reverse osmosis + Elettrodeionization (RO+ELDI) is a production system including a Pretreatment section to prepare the water to the following primary purification steps including RO unit before the final Elettrodeionization unit.


Applications


  • Pharmaceutical Water
  • USP: PW
  • EU Ph: PW


ELETTRACQUA Reverse osmosis + Elettrodeionization is used for the production of non-compendial and compendial Purified Water (PW) meeting the USP and European Pharmacopoeia requiremenys, several ELETTRACQUA Reverse Osmosis + Elettrodeionization system has been successfully validated across the world.

Construction features


Each ELETTRACQUA plant is “tailor made” to meet the different specificity of our customers requirements, or starting from customer room lay out to have the best installation solution.

Frame: AISI 304

Piping and fittings: AISI 316L ASME BPE

Connections: Tri-clamp

Membrane Housings: AISI 316L

Valves: AISI 316L

Sanitization


ELETTRACQUA Reverse osmosis + Elettrodeionization sanitization options are:


Chemical sanitization

Hot water sanitization

Hot Water sanitization


Elettracqua high temperature RO + ELDI are sanitized with hot water (> 80°C), having several advantages than chemical sanitization:

  • Sanitization process fully automatic managed by PLC with continuous monitoring of sanitization temperatures
  • Semplified validation of the thermal process
  • Reliable process
  • No need to prove the chemical rinse out

Compliance


CGMP

USP PW
EU Pharmacopoeia

ISPE Baseline Guide

GAMP 5

 
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